Sitting just outside of the bottom two, the green and whites will look to end a run of six straight defeats with a much-needed three points.
In a week which has seen the club confirm an agreed takeover subject to EFL approval, the attention now turns to the pitch for Darren Way’s side.
If fortunes are to turn it’ll be without defender Tom James who’ll serve the last of a four-match suspension, whilst Josh Grant (ankle), Sessi D’Almeida (shoulder) and Gary Warren (hamstring) will all remain sidelined.
Absent since September, Omar Sowunmi returned to training last week and could be pushing for inclusion when the U’s head to Somerset.
Whoever makes the matchday 18 will be up against a Cambridge side looking to bounce back from midweek defeat.
Colin Calderwood’s side lost 2-0 at Cheltenham on Tuesday night to remain three places and six points above the green and whites.
Saturday will be the 13th meeting between the two sides with Town boasting six wins to their name.
Winning the first five encounters between 1987 and 2004, the Glovers have since only won one of the last seven.
That victory came at Huish Park a year ago when Nathan Smith and Alex Fisher claimed a 2-0 win.
Graham Salisbury will be the man in charge this weekend.
His 27th match of the season, it’ll be his second involving the Glovers after overseeing the Boxing Day defeat at Exeter City.
Mr Salisbury will be assisted by Andrew Hendley and Steven Plane with Sam Allison acting as fourth official.
The pre-match thoughts of Nathan Baxter and manager Darren Way will be available on iFollow Glovers following their press conference on Friday afternoon.
If you’re unable to attend the game, overseas supporters can watch the game live via the iFollow Glovers service!
A full match report will follow on YTFC.net at full time with post-match reaction from the manager and a member of the playing staff following soon after.