Darren Way’s side will be looking to build on back-to-back wins away from home, having seen off Colchester and Coventry on their travels.
Re-arranged from last month, Town head to take on Swindon without Ryan Dickson and Francois Zoko who were both dismissed in the 3-0 loss to Luton at the weekend.
Left-back Dickson will serve his one-match suspension at the Country Ground whilst Zoko begins his four-match ban.
Their absence will see a reshuffle amongst the squad, with Corey Whelan, Connor Smith and Ryan Seager in line for potential recalls to the matchday 18.
For the Robins, they’ll be looking for their first win in five after three consecutive draws.
Phil Brown’s side drew 0-0 with Carlisle at home on Saturday and will be looking for Marc Richards (10 goals) to provide their goal threat.
Tuesday’s clash will be the 17th meeting between the two sides with Town boasting five wins to their name as well as three draws.
The Glovers last won at the County Ground in 2015 as James Berrett’s second half strike secured a 1-0 win.
Yeovil’s most dramatic win at Swindon came in 2008 with Craig Alcock, Lee Peltier and a Jerel Ifil own goal seeing Town come away 3-2 victors.
Trevor Kettle (Leicestershire) will be the man in the middle at the County Ground.
It will be his second match of the season involving Darren Way’s side, having overseen the 2-0 loss at Crawley in September.
Rob Smith (Hertfordshire) and Ron Ganfield (Somerset) will be his assists with Mark Derrien (Dorset) acting as fourth official.
On matchday, minute-by-minute updates will be provided on YTFC’s official Twitter account and live matchday centre.
If you’re unable to attend the game, live audio commentary is available via the iFollow Glovers service, with the monthly and season subscriptions offering full-match replays from Sunday.
A full match report will follow on YTFC.net at full time with post-match reaction from the manager and a member of the playing staff following soon after.