The Glovers entertain the O’s at Huish Park looking to build on their victory against high-flyers Plymouth Argyle last time out at home.
Harrison, who made his first start at Luton in midweek, is keen to use the vociferous support to his side’s advantage.
Speaking to YTFC’s official YouTube channel, he said: “We’ll challenge them, especially playing at home.
“We’ll have the crowd behind us which is an advantage so we’ll take that into the game.
“The crowd here are superb,” he continued. “They get behind us the whole way, good or bad result, and always believe in us. That really helps.”
The Tottenham loanee is enjoying his first taste of senior football, and hopes to build on his first 90 minutes for the Club on Tuesday night.
“I expected the physical side of it, which is something I’ve always wanted to improve in my game. It’s helping me being in men’s football.
“It’s a good league; a hard league with some good, good teams.
“The top teams are very good sides but our team and our squad are just as good and can beat anyone really.
“The most important thing is to deal with my side of the game first and go from there.”
Tickets are still available to purchase for Saturday’s fixture via the Huish Park ticket office either in person or by calling 01935 847888. Alternatively, tickets can be bought online.