Town welcome Keith Curle’s side to Somerset for the first of three home matches remaining in the 2016/17 Sky Bet League Two campaign.
Carlisle are winless in seven matches following a 2-0 defeat to Crewe Alexandra which saw them drop out of the play-offs for the first time since September.
The Cumbrians recorded their seventh consecutive victory at home in the reverse fixture against the Glovers, running out 2-1 winners at Brunton Park back in December.
Yeovil’s last home win over Carlisle came in 2011 with Jonathan Obika grabbing the game’s only goal.
Fans can purchase tickets for the match in person at the ticket office, online or by phone on 01935 847888.