The Glovers head to the Bob Lucas Stadium for their first pre-season fixture.
After a week of pre-season training, Town travel to Dorset for their first run out in preparation for the 2017/18 Sky Bet League Two season.
Yeovil last took on local rivals Weymouth in a behind closed doors friendly in 2013 running out 7-0 winners, with the last competitive fixture between the two sides coming in 1999 - an FA Trophy second round win for Town after a replay.
New recruits Rhys Browne, Connor Smith, Jake Gray, Stephane Zubar, James Bailey and Fela Olomola are all in line to feature for Darren Way's side, offering a first glimpse for the travelling Green and White faithful.
The clash with the Terras kick starts a busy pre-season period, with a further six matches to follow before the campaign begins in August.