A 76h minute winner from super sub Dean Bowditch gave Yeovil Town all three points at a windswept Huish Park this afternoon.
The striker, who had only arrived in the game five minutes beforehand, bundled in a Scott Murray free-kick after Murray had been fouled by Dougie Freedman.
The Shrimpers played an hour with ten men after Sean Morrison was red-carded for tugging down Jon Obika as he had passed the defender.
Manager Terry Skiverton made six changes from the side that lost last weekend. In goal, Alex McCarthy came in for Richard Martin while Danny Hutchins, George O'Callaghan, Scott Murray, Stefan Stam and Jean-Paul Kalala came in for Nathan Jones, Terrell Forbes, Keiran Murtagh, Shaun MacDonald and Sam Williams.
The first ten minutes saw the Glovers look a bit fragmented while both sides got used to a swirling wind.
The first sight of goal came the Shrimpers way when after twelve minutes, a nicely worked move down the right between Freedman and top scorer Lee Barnard set up Francis Laurent but the young Frenchman poked his near post shot into the side netting.
The Blues continued to look the equal of their hosts and forced their first corner somewhat fortuitously as Ryan Mason had been fouled in the build-up in midfield.
The hosts finally got going and came close to scoring on eighteen minutes. A far post corner from Scott Murray was headed against the post from full back Craig Alcock.
The two Yeovil flankmen were continually swapping sides giving the away defence something to think about constantly. All they could reply with were dangerous swirling set pieces from Simon Francis.
As conditions worsened and the wind picked up, so did Yeovil's effort and play. George O'Callaghan curled a lovely cross over that just eluded Murray before the Scots winger saw his shot saved by ex-Yeovil keeper Steve Mildenhall.
The 6'5" gloveman made an even better save minutes later when he got down low to turn around a Jon Obika effort.
On the half hour, Southend lost defender Morrison to a straight red card.
Ryan Mason, linking well with Spurs team-mate Obika, sent the big striker away only to see Morrison pull him down when through. Despite the protestations of the Southend team, referee Phillips had no option but to wave the red card at Morrison.
Mason curled the free kick inches wide though and the chance was gone but the dismissal galvanised Yeovil who then pushed forward oin waves before half-time.
Mildenhall denied Murray again before Welsh skimmed the top of the bar with a fierce rising shot.
The second half started as the first with both sides taking a while to readjust to the conditions before the first real sight of goal in the second period. Man-of-the-match Mason set Scott Murray free of the offside trap but the winger trod on the ball and hit his hurried shot wide of the goal.
Ten minutes later and the other winger Welsh found himself in acres of space too but delayed his effort and the Southend defence cleared as far as Murray whose shot was deflected for a corner.
This was Yeovil's best spell of the match and they had to make their pressure count. Kalala fired a shot wide and Murray curled a free-kick just past the post as the Glovers toiled without success.
Welsh was withdrawn on 71 minutes as manager Skiverton sent on Dean Bowditch for his first taste of League One football since the opening day victory over Tranmere.
It took only five minutes for the striker to make an impression though. Freedman and Murray clashed wide on the right earning Yeovil the free-kick. Murray swung it over and amidst the scramble, Bowditch bundled the ball in for his second goal in two appearances.
Gavin Tomlin came on for Murray and Murtagh replaced Mason as the home team secured the victory. Supersub Bowditch could well have notched a second but he fired one shot well wide before sliding in and seeing his attempt saved by Mildenhall.
Four minutes of stoppage time was seen off successfully and the Glovers now move up into twelfth leap-frogging today's opponents.